ISTP, 8025 Lamon Ave. Skokie, Il 60077

Purefast™ Home Filter for PFAS!

Cyclopure Inc. announced the commercial launch of its Purefast™ filters for PFAS removal from tap water. The home filter is compatible for use with Brita countertop pitchers, and has been certified by NSF International for PFAS removal. Filters will be priced at $45 with a capacity of 65 gallons, and replace 700 single use water bottles. The company has validated the removal of 11 PFAS compounds, including PFOS, PFOA, PFNA and GenX, to non-detect throughout the duration of the 65-gallon filter cycle.

“We are thrilled to bring Purefast to market, a first-ever product for use with countertop pitchers to remove PFAS,” said Cyclopure CEO Frank Cassou. “Purefast provides households with the ability to protect themselves from PFAS in a convenient and affordable manner.”

Filters are available now for pre-order on the company’s website, with first product shipments to begin on April 18, 2022. Products are made and fulfilled out of Cyclopure’s Skokie facility in the Illinois Science & Technology Park.

“Purefast is also going to be a valuable tool for communities impacted by PFAS,” said Cassou. “Town health boards will now have a quick and affordable solution to offer residents in the case of a PFAS contamination event.”

“Sustainability is a top priority for our water treatment applications,” added Cassou. “We use our DEXSORB® adsorbent made from renewable cyclodextrins for PFAS removal. Each Purefast filter comes with prepaid packaging to return used cartridges to our lab for safe disposal. On a scale of 0-10, Purefast is a Zero! Zero PFAS in your water, and Zero PFAS waste to the environment.”

Cyclopure’s development activities have benefited from years of funding and support from the National Science Foundation (NSF Grant 1831206) and the National Institute of Environmental Health Sciences (SRP Grant R44ES029401). NIEHS recently reported on the development of Purefast™ in the April 2022 edition of its online Environmental Factor newsletter.

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Cour Pharma Expands at ISTP

To meet the increasing demand for medical research space in the Chicagoland area, Cour Pharmaceuticals’ life science and emerging biotechnology footprint is expanding within the Illinois Science and Technology Park in Skokie, Ill. With the addition, Cour Pharmaceuticals now leases around 25,000 sq. ft. in the park.

COUR Pharmaceuticals is developing first-in-class therapies designed to reprogram the immune system to achieve antigen-specific tolerance for immune-mediated disease. COUR’s platform of immune-modifying nanoparticles treats the root cause of immune disease, unlike traditional approaches, which only minimize symptoms using toxic immune suppression.

“Continued rapid growth for high-potential life science startups are emerging in Chicago and in addition to talent, life sciences companies like COUR will continue to need access to more specialized wet and dry lab space along with capital,” said COUR Pharmaceuticals CEO John Puisis.

 

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ISTP Ownership Changes

These recent sales highlight property types for which real estate investors have clamored during the COVID-19 pandemic: high-quality life sciences research buildings and office buildings with big, single tenants with good credit and long-term leases. The former has benefited from a rush of venture capital pouring into biotech and pharmaceutical research throughout the public health crisis, while the latter has drawn buyers looking for safe places to invest amid economic uncertainty

A venture of Hallandale Beach, Fla.-based TopMed Realty bought the 233,588 -square-foot office building at 4901 Searle Parkway. The building, which is almost fully leased to NorthShore University HealthSystem on a long-term deal, was purchased from a venture of Skokie-based American Landmark Properties

The sale comes a month after American Landmark sold the life sciences lab portion (8025 and 8045 Lamon Ave.), the majority of the leased 22.6-acre ISTP campus to Chicago-based investor Singerman Real Estate. The portfolio is comprised of a mix of highly technical wet lab and GMP space and is home to established global life sciences brands as well as prestigious university affiliated venture backed startups.

Noted Sam DiFrancesca and Lucas Borges of the JLL Capital Markets team…. “We were encouraged by the depth of capital with an interest in Greater Chicago and are excited to see such an established national life sciences investor as Singerman committing to the market,” “The level of lender interest in this portfolio is further testament to Chicago’s significant growth potential within the life sciences space.” Max Zwolan and Scott Brandwein of JLL also supported the transaction and will continue to handle the leasing for the buyers.
For the entire article, click here.

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NU Record Research Funding

Northwestern Research Funding- Record $893M.  Northwestern University’s research enterprise once again demonstrated strong performance, with annual sponsored funds reaching a new record high of $893.4 million for the fiscal year that closed Aug. 31. This represents an increase of 1% from last year’s total and continues a decade-long trend that has positioned Northwestern among the nation’s most prestigious research institutions. Since 2011, the University’s research funding has increased more than 74% as Northwestern approaches $1 billion in sponsored support, a feat achieved by only its top academic peers.

“The remarkable depth and breadth of Northwestern research continues to make a huge positive impact, transforming entire fields and strengthening society,” Milan Mrksich, vice president for research. said. “As we continue to go from strength to strength — including important investments in our entrepreneurial and innovation ecosystem to increase translation — we will enhance our already superb research enterprise to keep elevating Northwestern’s reputation as a premier destination for the best scholars, scientists and students in the world.”

“Our research portfolio now includes a higher percentage of larger, complex awards, reflecting the collaborative approach to research that Northwestern fosters,” said Shandra White, executive director of Sponsored Research. “Having diverse projects within Northwestern’s research landscape is vital, along with the robust infrastructure to support the complexity of those high-impact investigations.”

For more about NU, click here.

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CMO Leadership Awards

Vetter was granted the 2021 CMO Leadership Awards in five core categories – quality, expertise, compatibility, capabilities, and service. Winning five core categories reaffirms Vetter as a trusted solution provider, particularly during globally challenging times.

“Yet again, Vetter is honored to be a winner of the CMO Leadership Awards as determined by our most important judges – our global customers,” said Vetter Managing Director Peter Soelkner. “This recognition is of particular importance given the challenging and turbulent times we are all experiencing with the global Covid-19 pandemic.” Carsten Press, Vetter’s Senior Vice President Key Account Management/Supply Chain Management/Marketing added, “Winning this award in five key categories is a direct reflection of what we strive to project to our customers. It further demonstrates our stable performance for them and especially their patients.”

Unlike other awards where an application process takes place, winners of the CMO Leadership Awards are chosen according to a customer ranking system. The basis for this is their hands-on experience with the service providers they have actually worked with. Using this method of validation means results are not able to be influenced in any manner. As such, the awards honor true customer performance and signify that winning companies have distinguished themselves through a leading level of support for the needs of their pharma and biotech customers.

To read the entire release, click here

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Demand for Lab Space

A surge in life sciences funding has spiked the demand for lab space. While the pandemic and the race for a vaccine certainly accelerated investor interest, it was already ignited by ongoing breakthroughs in immuno-oncology, neonatology and other technological advances. What’s more, investment in the sector has translated into commercial real estate leasing in a clear and direct way.

This has impacted leasing. In the major U.S. life sciences markets, total vacancy has decreased by 250 basis points between 2015 and 2020, from 9.8 percent to 7.3 percent. The pandemic is a major driver of the increased government funding. In the U.S., Project Warp Speed sent billions toward COVID-19 research and biomanufacturing with the intent of bringing a vaccine to market.

These transactions bring with them a plethora of life sciences jobs, which can also spur development of housing, retail and other urban amenities that serve the people who live and work in the knowledge center.

“Every time there is a funding round, it’s only a matter of months before these companies are looking for new space,” says Travis McCready, Executive Director, US Life Sciences Markets, JLL. “When companies get VC money, they need lab space in order to deliver as soon as humanly possible. Life sciences have an outsized impact on development in the surrounding area when compared to other sectors,” McCready says. “In a sense, increased investment in life sciences is the tide that lifts all ships” To learn more from JLL, click here.

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8-Story Hotel In Downtown Skokie

The 142-room Homewood Suites by Hilton is planned for the northeast corner of Oakton Street and Niles Avenue. The deal calls for the developer to present proof that a hotel at least as prestigious as a Homewood Suites plans to operate at the site for at least 15 years.

The hotel is set to include 30,000 square feet of retail space on its ground floor and rooftop and about 10,000 square feet of banquet and event space.

Corporation Counsel Michael Lorge said the project will be a positive addition to the under-construction 8000 North development about 1,000 feet to the west on Oakton Avenue.  “The addition of a hotel to the downtown area is an important and a commanding addition to the economic development already going on in downtown Skokie, and it provides great resources for the surrounding corridor,” Lorge said ahead of the project’s approval at the Dec. 7 village board meeting. “It is also an important addition to the Illinois Science and Technology Park, which needs hotel accommodations for its tenants.”

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DEXSORB Absorbent Update

Cyclopure continues to move its NSF 61-certified DEXSORB® adsorbent forward for use in environmental applications for the removal of PFAS from water supplies.

The company has recently signed on to several new pilot installations for groundwater remediation and the treatment of wastewater effluent and drinking water supplies, with two deployments planned for the fourth quarter of 2021.

Cyclopure continues to move its NSF 61-certified DEXSORB® adsorbent forward for use in environmental applications for the removal of PFAS from water supplies. The company has recently signed on to several new pilot installations for groundwater remediation and the treatment of wastewater effluent and drinking water supplies, with two deployments planned for the fourth quarter of 2021.

Cyclopure’s skid-mounted pilot systems, in a lead-lag vessel configuration, will provide full-scale demonstration of PFAS removal performance. Pilot activities will also encompass full treatment train capabilities of spent media regeneration and destruction of the isolated PFAS waste stream.

For more about Cyclopure, click here.

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Chicago Area Life Science Cluster

A life sciences cluster has also grown in recent years in and around Chicago, where three federal laboratories, several biopharma giants, and an emerging community of startups are buttressed by a strong base of academic research institutions—including Northwestern University, the University of Chicago, and the University of Illinois.

The bioscience industry’s economic footprint reaches into so many local communities across the country. From capital investments to research & development, this report shows the impact of the biosciences across the nation’s innovation ecosystem.

In Illinois, life sciences employers grew their employment base since 2016, increasing by 3.2 percent reaching nearly 88,000 direct jobs. Research also ranked in the top tier of all states in life sciences related academic R&D activities. Illinois research institutions spent nearly $1.6 billion in 2018 on R&D.

“The bioscience industry is critically important to Illinois and we are proud to work closely with partners like iBIO to help ensure the future of the industry and its role as an economic driver in the region,” said Pete Pellerito, BIO Senior Policy Adviser for Federal and State Economic Development and Technology Transfer Initiatives. To access the entire article, click here.

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Cyclopure Commercialization

The team aims to take their technology into several markets. There is the consumer point-of-use market (think of home systems that use carbon to purify water). The company plans to sell branded products through its e-commerce website.

In parallel with commercialization of the first generation of water treatment products, the company continues to invest heavily in research and development to improve the performance and value of its cyclodextrin adsorbents. Cyclopure’s scientists have modified their cyclodextrin adsorbents to target specific contaminants. After targeting pharmaceuticals and pesticides with its technology, the company’s chemists designed a second adsorbent named, DEXSORB+ and will be used for municipal applications. Today, its pilot scale production at the lab is producing 60 kilograms per month, enabling them to push out its commercial products, analytical and home activities. The company is launching its second home water test kit for pharmaceuticals and pesticides.

“If we can get people to trust in their tap again, with a cost effective solution, it’s a home run for everybody,” Frank Cassou, chief executive officer of Cyclopure said. “We are all trying to preserve water, be efficient in times where there’s growing populations. We want to bring a solution to the household that is healthy, affordable, and sustainable.”

For more insights on Cyclopure, click here.

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